Kim Possible is a teenage girl starting her first year of high school, who after answering a distress call began a career as a crimefighter along with her best friend and sidekick, Ron Stoppable.
In Europe, American high school students and crimefighters Kim Possible and Ron Stoppable have thwarted a world dominating scheme of Professor Dementor and rescued his captive Dr. Glopman.
As Kim and Ron start their first day of school, they meet a new student named Athena and take her on a mission to stop the plot of the evil Dr. Drakken. Athena defeats Dr. Drakken's abettor Shego, making her the topic of conversation at Middleton High School. Kim deals with personal issues and her limitations as a teenage crimefighter.
When the school honors Athena and her good deed, Shego and Dr. Drakken force their way into the ceremony. Kim tries to defeat Shego and her army of henchwomen but falls to the ground, leaving Athena vulnerable to capture. Athena is taken away and Kim is laughed at. After Kim talks with her family and Ron, they decide to rescue Athena from Drakken's and Shego's lair.
At the lair, Kim discovers Athena is part of Drakken's and Shego's plan to steal Kim's motivational essence and transfer it into Drakken using his brain-modulating device. Athena is revealed to be a gynoid built by Drakken. As Kim short-circuits the transfer machine, Dr. Drakken is turned into a pre-adolescent version of himself. Despite Kim's insistence that she leaves with them and save herself, Athena stays behind to turn off the now-unstable machine. The lair explodes and Athena is presumed killed but it is revealed that she has survived the explosion but her robotic parts are scattered. Kim and Ron take her home to be repaired and programmed to be a hero alongside themselves.
- Kim is portrayed by Sadie Stanley.